​Cells Apoptosis

Apoptosis is a fundamental biological phenomenon of cells and plays a necessary role in the removal of unwanted or abnormal cells by multicellular organisms. It plays an important role in the evolution of organisms, the stability of the internal environment, and the development of multiple systems. Apoptosis is divided into different stages.

1.early apoptosis
The first characteristic of early apoptosis was the medial eversion of the lipid membrane, and the detection index was Annexin V
The second characteristic of early apoptosis: mitochondrial membrane potential changes, detection index: JC-1.
The third characteristic of early apoptosis was the activation of mitochondrial permeability transition pore (MPTP), as measured by MPTP.
2. metaphase apoptosis
Caspase activation causes apoptosis-related changes, including three mechanisms: cleavage of apoptosis inhibitor to activate nucleases; Destruction of cell structure; Regulation of protein function.
3.late apoptosis
Late apoptosis is characterized by chromosomal DNA fragmentation; Detection index: Tunel staining.
KTA4001   Mitochondrial Membrane Potential Assay Kit (JC-1)
KTA4002   Mitochondrial Permeability Transition Pore Assay
KTA0001   Annexin V-AbFluor™ 405 Apoptosis Detection kit (Blue Fluorescence)
KTA0002   Annexin V-AbFluor™ 488/PI Apoptosis Detection kit
KTA0003   Annexin V-AbFluor™ 555 Apoptosis Detection kit (Orange Fluorescence)
KTA0004   Annexin V-AbFluor™ 647 Apoptosis Detection kit (Red Fluorescence)
KTA0005   Annexin V-EGFP/PI Apoptosis Detection kitKTA2010​   One-step TUNEL Apoptosis Assay Kit (Green Fluorescence)
KTA2011   One-step TUNEL Apoptosis Assay Kit (Orange Fluorescence)
KTA3020   Caspase-1 Assay Kit (Colorimetric)
KTA3021   Caspase-2 Assay Kit (Colorimetric)
KTA3022   Caspase-3 Assay Kit (Colorimetric)
KTA3023   Caspase-4 Assay Kit (Colorimetric)
KTA3024   Caspase-6 Assay Kit (Colorimetric)
KTA3025   Caspase-8 Assay Kit (Colorimetric)
KTA3026   Caspase-9 Assay Kit (Colorimetric)